Submitted by: Eduardo Nunez
Hospitalized or fatal COVID-19 vaccine breakthrough cases reported to CDC as of June 21, 2021
As of June 21, 2021, more than 150 million people in the United States had been fully vaccinated against COVID-19.
During the same time, CDC received reports from 47 U.S. states and territories of 4,115 patients with COVID-19 vaccine breakthrough infection who were hospitalized or died.
| Hospitalized or fatal vaccine breakthrough cases reported to CDC | 4,115 | |
|---|---|---|
| Female | 2,001 | (49%) |
| People aged ≥65 years | 3,124 | (76%) |
| Asymptomatic infections | 750 | (18%) |
| Hospitalizations* | 3,907 | (95%) |
| Deaths† | 750 | (18%) |
*1,004 (26%) of 3,907 hospitalizations reported as asymptomatic or not related to COVID-19.
†142 (19%) of 750 fatal cases reported as asymptomatic or not related to COVID-19.
†142 (19%) of 750 fatal cases reported as asymptomatic or not related to COVID-19.
Previous data on all vaccine breakthrough cases reported to CDC from January–April 2021 are available.
How to interpret these data
The number of COVID-19 vaccine breakthrough infections reported to CDC likely are an undercount of all SARS-CoV-2 infections among fully vaccinated persons. National surveillance relies on passive and voluntary reporting, and data might not be complete or representative. These surveillance data are a snapshot and help identify patterns and look for signals among vaccine breakthrough cases.
Data on patients with vaccine breakthrough infection who were hospitalized or died will be updated regularly. Studies are being conducted in multiple U.S. sites that will include information on all vaccine breakthrough infections regardless of clinical status to supplement the national surveillance.
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